SCHEMBL6721772

SCHEMBL6721772

Cc1nc(N)c2nc(C)n(CCCCC(N)=O)c2c1C

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 5/20 0.37
CSNK2A2 P19784 3/20 0.37
CSNK2B P67870 3/20 0.37
CSNK2A3 Q8NEV1 3/20 0.37
PIM1 P11309 1/20 0.37
DYRK1A Q13627 3/20 0.35
TLR7 Q9NYK1 5/20 0.33
FAAH O00519 3/20 0.32
PNP P00491 1/20 0.31
HSP90AA1 P07900 2/20 0.31
HDAC1 Q13547 2/20 0.30
HDAC6 Q9UBN7 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6820241 0.95 CSNK2A1 (0.37) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL6724656 0.83 TLR7 (0.44) TLR7
SCHEMBL5617200 0.82 TLR7 (0.40) DYRK1ATLR7
SCHEMBL6097458 0.81 CSNK2A1 (0.55) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL4791595 0.81 CSNK2A1 (0.37) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL6721688 0.81 CSNK2A1 (0.37) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL6094589 0.81 DYRK1A (0.37) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL6729448 0.80 CSNK2A1 (0.36) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL4792051 0.80 CSNK2A1 (0.36) CSNK2A1CSNK2A2CSNK2BCSNK2A3PIM1
SCHEMBL5617062 0.80 TLR7 (0.43) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040019076-A1 SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY 2004-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019076-A1 SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES IRF3, EIF2AK2, MYD88 CSNK2A1 1056/4885CSNK2A2 1302/4885CSNK2B 1845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.