⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866328 | 0.83 | — | — | |
| SCHEMBL3588077 | 0.77 | — | — | |
| SCHEMBL8990992 | 0.73 | — | — | |
| SCHEMBL4394182 | 0.73 | — | — | |
| SCHEMBL5424388 | 0.71 | — | — | |
| SCHEMBL4390917 | 0.71 | — | — | |
| SCHEMBL3297413 | 0.69 | — | — | |
| SCHEMBL6161595 | 0.69 | — | — | |
| SCHEMBL6355264 | 0.69 | — | — | |
| SCHEMBL3579303 | 0.67 | CYP3A4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | claimed |
| US-20160145197-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. | 2016-05-26 | — | — | US | claimed |
| EP-2870132-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | AbbVie Inc. (US) | 2015-05-13 | — | — | EP | claimed |
| US-20140012015-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. | 2014-01-09 | — | — | US | claimed |
| WO-2014008350-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. (US) | 2014-01-09 | — | — | WO | claimed |
| US-20130303549-A1 | NOVEL BIAROMATIC COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF | GALDERMA RES & DEV (FR) | 2013-11-14 | — | — | US | claimed |
| US-8513297-B2 | Biaromatic compounds that modulate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-08-20 | — | — | US | claimed |
| US-20120121527-A1 | NOVEL BIAROMATIC COMPOUNDS THAT MODULATE PPARy TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-05-17 | — | — | US | claimed |
| US-8129416-B2 | Biaromatic compounds that modulate PPARgamma type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-03-06 | — | — | US | claimed |
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | THE KITASATO INSTITUTE (JP) | 2011-07-28 | — | — | US | claimed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | claimed |
| EP-0700914-A1 | Camptothecin derivatives, preparations thereof and antitumor agents | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1996-03-13 | — | — | EP | claimed |
| EP-0656356-A1 | DIOXACYCLOALKANE COMPOUND WITH RENIN-INHIBITING ACTIVITY | JAPAN TOBACCO INC. (JP) | 1995-06-07 | — | — | EP | claimed |
| US-5411737-A | Flea and tick collars | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | claimed |
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | claimed |
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | claimed |
| US-4929637-A | CARBONIC ANHYDRASE INHIBITORS, VISION DEFECTS | MERCK & CO., INC. (US) | 1990-05-29 | — | — | US | claimed |
| EP-0228237-B1 | SUBSTITUTED THIOPHENE-2-SULFONAMIDE ANTIGLAUCOMA AGENTS | MERCK & CO. INC. (US) | 1989-11-23 | — | — | EP | claimed |
| EP-0228237-A1 | Substituted thiophene-2-sulfonamide antiglaucoma agents | MERCK & CO. INC. (US) | 1987-07-08 | — | — | EP | claimed |
| US-4174345-A | TREATMENT OF STEROL ETHERS WITH ZINC BROMIDE IN METHYLENE CHLORIDE | KAISER EMIL T | 1979-11-13 | — | — | US | claimed |