SCHEMBL672340

SCHEMBL672340

C/C=C(\C)C(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 6/20 0.50
MAPT P10636 3/20 0.47
SLC6A2 P23975 3/20 0.47
SLC6A3 Q01959 3/20 0.47
HPGD P15428 2/20 0.47
NR1I2 O75469 1/20 0.47
LMNA P02545 1/20 0.47
PGR P06401 1/20 0.47
HSP90AA1 P07900 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
HSPA5 P11021 1/20 0.47
CBR1 P16152 1/20 0.47
TBXA2R P21731 1/20 0.47
AGTR1 P30556 1/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PLA2G1B P04054 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30970223 0.85 TTR (0.52) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL677375 0.85 TTR (0.52) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL2040582 0.83 TTR (0.56) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL13408233 0.81 TTR (0.51) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL10320457 0.77 TTR (0.54) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL7072347 0.77 TTR (0.52) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL2281050 0.77 TTR (0.50) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL10320786 0.76 TTR (0.55) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL13390195 0.76 TTR (0.43) TTRMAPTSLC6A2SLC6A3HPGD
SCHEMBL21766842 0.75 TTR (0.38) TTRMAPTSLC6A2SLC6A3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011142935-A1 METHODS AND APPARATUS FOR A TRANSPARENT AND FLEXIBLE FORCE-SENSITIVE TOUCH PANEL SYMBOL TECHNOLOGIES, INC. (US) 2011-11-17 WO disclosed
US-8053535-B2 Polysiloxanes with anti-fouling activity NDSU RESEARCH FOUNDATION (US) 2011-11-08 US disclosed
EP-1856207-A4 POLYSILOXANES WITH ANTI-FOULING ACTIVITY NDSU RES FOUNDATION (US) 2009-07-01 EP disclosed
US-20090018276-A1 Polysiloxanes with anti-fouling activity NDSU RESEARCH FOUNDATION 2009-01-15 US disclosed
EP-1856207-A2 POLYSILOXANES WITH ANTI-FOULING ACTIVITY NDSU Research Foundation (US) 2007-11-21 EP disclosed
WO-2007053163-A2 POLYSILOXANES WITH ANTI-FOULING ACTIVITY NDSU RESEARCH FOUNDATION (US) 2007-05-10 WO disclosed