SCHEMBL6724420

SCHEMBL6724420

O=c1[nH]nc2ccc(C(F)(F)F)cn12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 2/20 0.55
NOTUM Q6P988 5/20 0.49
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP1A2 P05177 1/20 0.39
USP7 Q93009 1/20 0.38
RXFP1 Q9HBX9 2/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36
AKR1B1 P15121 1/20 0.36
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251575 0.87 SCN5A (0.68) SCN5ANOTUM
SCHEMBL16154734 0.83 SCN5A (0.48) SCN5ANOTUMKDM4EALDH1A1HSD17B10
SCHEMBL20772490 0.77 SCN5A (0.51) SCN5ANOTUM
SCHEMBL24087822 0.76 SCN5A (0.51) SCN5ANOTUMKDM4EALDH1A1TDP1
SCHEMBL23057535 0.75 CYP1A2 (0.44) SCN5ANOTUMCYP1A2USP7MEN1
SCHEMBL252266 0.73 SCN5A (0.48) SCN5ANOTUMKDM4ERXFP1POLB
SCHEMBL20773134 0.72 SCN5A (0.48) SCN5ANOTUMTDP1
SCHEMBL17403215 0.72 TDP1 (0.47) SCN5ANOTUMTDP1
SCHEMBL24087890 0.71 SCN5A (0.43) SCN5ANOTUMCYP1A2
SCHEMBL248547 0.71 SCN5A (1.00) SCN5ANOTUMPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019043635-A1 D-AMINO ACID OXIDASE ACTIVITY INHIBITING COMPOUNDS RICHTER GEDEON NYRT. (HU) 2019-03-07 WO claimed
US-20260101898-A1 SULFONAMIDE COMPOUND AND HARMFUL-ARTHROPOD CONTROLLING COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-04-16 US disclosed
US-11690378-B2 Substituted pyridines as noxious arthropod control agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-04 US disclosed
CN-113747783-B Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2022-10-11 CN disclosed
EP-3928607-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-29 EP disclosed
US-20210380610-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-09 US disclosed
US-20210059255-A1 HETEROCYCLIC COMPOUNDS AND NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-04 US disclosed
EP-3733667-A1 HETEROCYCLIC COMPOUNDS AND NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-11-04 EP disclosed
WO-2019043635-A1 D-AMINO ACID OXIDASE ACTIVITY INHIBITING COMPOUNDS RICHTER GEDEON NYRT. (HU) 2019-03-07 WO disclosed
US-20040063580-A1 Bicyclic triazolone derivatives and a herbicides containing the same SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2004-04-01 US disclosed
EP-1333031-A1 BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME Sumitomo Chemical Takeda Agro Company, Limited (JP) 2003-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11690378-B2 Substituted pyridines as noxious arthropod control agents COX6C, C5, COX6B1 SCN5A 1578/4885NOTUM 2729/4885KDM4E 1244/4885
US-20210059255-A1 HETEROCYCLIC COMPOUNDS AND NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING SAME C5, COX6C, C3AR1 SCN5A 1520/4885NOTUM 2007/4885KDM4E 2310/4885
US-20210380610-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME C5, COX6C, C3AR1 SCN5A 1513/4885NOTUM 3776/4885KDM4E 2743/4885
US-20040063580-A1 Bicyclic triazolone derivatives and a herbicides containing the same WEE1, WEE2, BAK1 SCN5A 2799/4885NOTUM 219/4885KDM4E 1331/4885
US-20260101898-A1 SULFONAMIDE COMPOUND AND HARMFUL-ARTHROPOD CONTROLLING COMPOSITION CONTAINING SAME COX6B1, CYC1, COX6C SCN5A 504/4885NOTUM 2194/4885KDM4E 2896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.