Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287372 | 0.89 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL19954527 | 0.77 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL5584120 | 0.74 | KLKB1 (0.69) | TRPV1 | |
| SCHEMBL31522202 | 0.74 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL2688412 | 0.74 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL14996588 | 0.73 | NPY5R (0.54) | TRPV1 | |
| SCHEMBL14659672 | 0.70 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL14659139 | 0.70 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL2688414 | 0.70 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL672566 | 0.70 | TRPV1 (0.51) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638034-A1 | SUBSTITUTED HETEROAROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062462-A1 | SUBSTITUTED HETEROAROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2012-05-18 | — | — | WO | disclosed |