Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6731633 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6735588 | 0.93 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6731522 | 0.93 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6723643 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6550640 | 0.91 | KMT2A (0.47) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6549184 | 0.90 | KMT2A (0.46) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6728640 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6722992 | 0.89 | KMT2A (0.46) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6728399 | 0.89 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AF2PRSS1PRSS2 | |
| SCHEMBL6730762 | 0.88 | F2 (0.47) | SMN1; SMN2KMT2AF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224251-A1 | Positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6548220-B2 | Containing acid generator | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |