Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736134 | 0.96 | CYSLTR1 (0.40) | CYSLTR1PTPN2PTPN1HTTTHRB | |
| SCHEMBL6734717 | 0.96 | CYSLTR1 (0.40) | CYSLTR1PTPN2PTPN1HTTTHRB | |
| SCHEMBL6731526 | 0.96 | CYSLTR1 (0.40) | CYSLTR1PTPN2PTPN1HTTTHRB | |
| SCHEMBL6723866 | 0.96 | CYSLTR1 (0.40) | CYSLTR1PTPN2PTPN1HTTTHRB | |
| SCHEMBL6729617 | 0.96 | CYSLTR1 (0.40) | CYSLTR1PTPN2PTPN1HTTTHRB | |
| SCHEMBL6731686 | 0.96 | CYSLTR1 (0.40) | CYSLTR1PTPN2PTPN1HTTTHRB | |
| SCHEMBL13090056 | 0.93 | CYSLTR1 (0.40) | CYSLTR1HTTTHRBNFKB1NFKB2 | |
| SCHEMBL12731853 | 0.92 | HTT (0.44) | PTPN2PTPN1HTTTHRBMEN1 | |
| SCHEMBL815840 | 0.92 | HTT (0.44) | PTPN2PTPN1HTTTHRBMEN1 | |
| SCHEMBL12731850 | 0.92 | HTT (0.44) | PTPN2PTPN1HTTTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154981-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2004-07-21 | — | — | EP | disclosed |
| US-6676851-B1 | LOW MELTING, GOOD ALIGNMENT ARYL BRANCHED ETHER-ESTER LINKED DIACRYLATES; REMAIN STABLE DURING COATING AND CROSSLINKING | ROLIC AG (CH) | 2004-01-13 | — | — | US | disclosed |