SCHEMBL672908

SCHEMBL672908

CC(C)CC(=O)N1CC1C

nearest known ligand 0.96

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.96
POLB P06746 3/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
GAA P10253 1/20 0.38
CA2 P00918 1/20 0.36
KDM4E B2RXH2 1/20 0.35
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20983243 0.87 SMN1; SMN2 (0.73) SMN1; SMN2POLBTSHRMAPTNPSR1
SCHEMBL17066206 0.85 SMN1; SMN2 (0.70) SMN1; SMN2POLBMAPTNPSR1L3MBTL1
SCHEMBL17066208 0.85 SMN1; SMN2 (0.70) SMN1; SMN2POLBMAPTNPSR1L3MBTL1
SCHEMBL19750306 0.82 SMN1; SMN2 (0.66) SMN1; SMN2POLBNPSR1L3MBTL1
SCHEMBL19750285 0.82 SMN1; SMN2 (0.66) SMN1; SMN2POLBNPSR1L3MBTL1
SCHEMBL31329108 0.82 SMN1; SMN2 (0.70) SMN1; SMN2TSHR
SCHEMBL12938733 0.78 SMN1; SMN2 (0.62) SMN1; SMN2TSHRMAPTGAA
SCHEMBL15854293 0.78 SMN1; SMN2 (0.61) SMN1; SMN2POLBNPSR1L3MBTL1GAA
SCHEMBL15490023 0.78 SMN1; SMN2 (0.61) SMN1; SMN2POLBNPSR1L3MBTL1GAA
SCHEMBL15490028 0.78 SMN1; SMN2 (0.61) SMN1; SMN2POLBNPSR1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
WO-2022124058-A1 POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE 株式会社ブリヂストン 2022-06-16 WO disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
US-10875937-B2 Terminal-modified conjugated diene polymer, rubber composition and rubber article BRIDGESTONE CORPORATION (JP) 2020-12-29 US disclosed
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20190161571-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT AND METHOD FOR MANUFACTURING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER BRIDGESTONE CORPORATION (JP) 2019-05-30 US disclosed
EP-3466985-A1 TERMINALLY MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT, AND METHOD FOR PRODUCING TERMINALLY MODIFIED CONJUGATED DIENE POLYMER Bridgestone Corporation (JP) 2019-04-10 EP disclosed
EP-3456746-A1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE Bridgestone Corporation (JP) 2019-03-20 EP disclosed
CN-106604935-B Method for producing terminal-modified conjugated diene polymer, rubber composition, and tire 株式会社普利司通 2019-02-22 CN disclosed
US-20100160530-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE BRIDGESTRONE CORPORATION (JP) 2010-06-24 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
CN-100554285-C Modified conjugated diene copolymer, rubber combination and tire BRIDGESTONE CORP (JP) 2009-10-28 CN disclosed
CN-101370867-A Rubber composition containing modified polybutadiene rubber and tire BRIDGESTONE CORP (JP) 2009-02-18 CN disclosed
EP-1975200-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE Bridgestone Corporation (JP) 2008-10-01 EP disclosed
US-20080177017-A1 Modified Polymer, Rubber Composition, and Tire BRIDGESTONE CORPORATION (JP) 2008-07-24 US disclosed
CN-101160328-A Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORP (JP) 2008-04-09 CN disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
CN-101094875-A Modified polymer, rubber composition, and tire BRIDGESTONE CORP (JP) 2007-12-26 CN disclosed
EP-1834966-A1 MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2007-09-19 EP disclosed