Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763001 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8763845 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5953816 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8763955 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8762989 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8763010 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8763096 | 1.00 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8086131 | 0.98 | TSHR (0.60) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28573156 | 0.98 | TSHR (0.60) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Trimethylammonium SCHEMBL27879354 | 0.94 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153899-B2 | Molding composition including an impact modifier derived from a silicone rubber monomer, a branched acrylate rubber such as isooctyl acrylate, and a graft link monomer; moldings with outdoor applications such as building materials | GENERAL ELECTRIC COMPANY (US) | 2006-12-26 | — | — | US | claimed |
| JP-2006518003-A | — | — | 2006-08-03 | — | — | JP | claimed |
| EP-1611187-A1 | SILICON-ACRYLATE IMPACT MODIFIER | GENERAL ELECTRIC COMPANY (US) | 2006-01-04 | — | — | EP | claimed |
| US-20050010001-A1 | Silicone-acrylate impact modifier and method for their preparation | GENERAL ELECTRIC COMPANY | 2005-01-13 | — | — | US | claimed |
| WO-2004074349-A1 | SILICON-ACRYLATE IMPACT MODIFIER | GENERAL ELECTRIC COMPANY (US) | 2004-09-02 | — | — | WO | claimed |
| US-20040162399-A1 | impact modifier composition comprises structural units derived from: at least one silicone rubber monomer, a branched acrylate rubber monomer | GENERAL ELECTRIC COMPANY | 2004-08-19 | — | — | US | claimed |
| EP-3640275-B1 | CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF | SHPP GLOBAL TECH BV (NL) | 2022-06-29 | — | — | EP | disclosed |
| EP-3289016-B1 | FLAME RETARDANT COMPOSITION, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-10-21 | — | — | EP | disclosed |
| US-10662312-B2 | Flame retardant composition, methods of manufacture thereof and articles comprising the same | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-05-26 | — | — | US | disclosed |
| EP-3640275-A1 | CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF | SABIC Global Technologies B.V. (NL) | 2020-04-22 | — | — | EP | disclosed |
| CN-111040130-A | Curable high heat epoxy compositions, cured epoxy compositions thereof, methods of manufacture thereof, and articles comprising the same | 沙特基础工业全球技术有限公司 | 2020-04-21 | — | — | CN | disclosed |
| US-20200115544-A1 | CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2020-04-16 | — | — | US | disclosed |
| CN-107531988-B | Flame retardant compositions, methods of making, and articles comprising the same | 沙特基础工业全球技术有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-20060004154-A1 | Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof | CITIBANK, N.A., AS COLLATERAL AGENT | 2006-01-05 | — | — | US | disclosed |
| WO-2005066278-A1 | POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050010001-A1 | Silicone-acrylate impact modifier and method for their preparation | GENERAL ELECTRIC COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-5427887-A | Blend of a diazo resin and an alkali soluble and swellable polymer | KONICA CORPORATION (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0583962-A2 | Light-sensitive composition | KONICA CORPORATION (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-4150945-A | AND AN AMINO ACID CURING AGENT | SANYO TRADING CO., LTD. (JP) | 1979-04-24 | — | — | US | disclosed |
| US-4069214-A | ACRYLIC ESTER POLYMER, AMINO ACID CURING AGENT, COATING METALS, BONDING PLYWOOD, FINISHING TEXTILES | SANYO TRADING CO., LTD. (JA) | 1978-01-17 | — | — | US | disclosed |