Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730073 | 0.79 | AOC3 (0.34) | FASNSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6730746 | 0.77 | HDAC2 (0.37) | FASNHDAC2 | |
| SCHEMBL3701259 | 0.71 | FASN (0.42) | FASNHTR2A | |
| SCHEMBL3700861 | 0.70 | FASN (0.42) | FASNHTR2A | |
| SCHEMBL6730692 | 0.70 | FASN (0.42) | FASNHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3692104 | 0.69 | TP53 (0.45) | FASNHTR2A | |
| SCHEMBL3698083 | 0.69 | HTR2A (0.42) | FASNHTR2AACHEHTR4ABL1 | |
| SCHEMBL13604749 | 0.68 | CACNA2D1 (0.47) | FASNOPRM1 | |
| SCHEMBL3696842 | 0.68 | BRAF (0.41) | FASNHTR2AACHEHTR4ABL1 | |
| SCHEMBL3692989 | 0.68 | HTR2A (0.52) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851199-B1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMA INC (US) | 2012-05-16 | — | — | EP | disclosed |