Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205786 | 1.00 | CYP2E1 (0.54) | CYP2E1NR1I2 | |
| SCHEMBL15498384 | 0.92 | CYP2E1 (0.45) | CYP2E1NR1I2 | |
| SCHEMBL15511997 | 0.92 | CYP2E1 (0.45) | CYP2E1NR1I2 | |
| SCHEMBL15498381 | 0.91 | CYP2E1 (0.55) | CYP2E1NR1I2 | |
| SCHEMBL15498383 | 0.85 | CYP2E1 (0.61) | CYP2E1NR1I2 | |
| SCHEMBL15498302 | 0.85 | CYP2E1 (0.61) | CYP2E1NR1I2 | |
| SCHEMBL15498382 | 0.83 | CYP2E1 (0.46) | CYP2E1NR1I2 | |
| SCHEMBL670676 | 0.83 | CYP2E1 (0.46) | CYP2E1NR1I2 | |
| SCHEMBL14718058 | 0.82 | NR1I2 (0.61) | CYP2E1NR1I2 | |
| SCHEMBL102096 | 0.82 | NR1I2 (0.61) | CYP2E1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606041-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | Vertex Pharmaceuticals Incorporated (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024363-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-02-23 | — | — | WO | disclosed |