⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260378 | 0.78 | — | — | |
| SCHEMBL16722800 | 0.77 | — | — | |
| SCHEMBL6623372 | 0.75 | — | — | |
| SCHEMBL10403168 | 0.74 | — | — | |
| SCHEMBL3865966 | 0.74 | — | — | |
| SCHEMBL10403166 | 0.74 | — | — | |
| SCHEMBL18827449 | 0.72 | — | — | |
| SCHEMBL8467419 | 0.72 | — | — | |
| SCHEMBL11052008 | 0.72 | — | — | |
| SCHEMBL2256069 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597926-B2 | Thiophosphoramidites | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-03-07 | — | — | US | claimed |
| CN-114206389-A | Multivalent ligand clusters for targeted delivery of therapeutic agents | 有丝分裂疗法有限责任公司 | 2022-03-18 | — | — | CN | claimed |
| US-20210115438-A1 | NOVEL THIOPHOSPHORAMIDITES | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-04-22 | — | — | US | claimed |
| EP-3728590-A1 | NOVEL THIOPHOSPHORAMIDITES | Roche Innovation Center Copenhagen A/S (DK) | 2020-10-28 | — | — | EP | claimed |
| CN-111448316-A | Novel thiophosphorous acid amides | 罗氏创新中心哥本哈根有限公司 | 2020-07-24 | — | — | CN | claimed |
| EP-2170353-B1 | PHOSPHATE-MODIFIED OLIGONUCLEOTIDE ANALOGS WITH IMMUNOSTIMULATORY ACTIVITY | ADIUTIDE PHARMACEUTICALS GMBH (DE) | 2015-06-03 | — | — | EP | claimed |
| US-6194398-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS, HERPES SIMPLEX VIRUS, HEPATITIS B VIRUS; ANTITUMOR AGENTS; SIDE EFFECT REDUCTION; ORAL ABSORPTION BIOAVAILABILITY; A 2-AMINO-6-HYDROCARBYLTHIO-9-(2-(PHOSPHONOMETHOXY)ETHYL-9H-PURINE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-02-27 | — | — | US | claimed |
| CN-118286449-A | Oligomer and oligomer conjugate | 豪夫迈·罗氏有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118116478-A | Nucleic acid-based data storage | 特韦斯特生物科学公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-112274647-B | Oligomer and oligomer conjugate | 豪夫迈·罗氏有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-110892485-B | Nucleic acid-based data storage | 特韦斯特生物科学公司 | 2024-03-22 | — | — | CN | disclosed |
| US-20240035032-A1 | OLIGOMERS AND OLIGOMER CONJUGATES | HOFFMANN-LA ROCHE INC. (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230287035-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF MICRORNA RELATED DISEASES | HOFFMANN-LA ROCHE INC. (US) | 2023-09-14 | — | — | US | disclosed |
| WO-1999064434-A1 | SYNTHETIC METHODS AND INTERMEDIATES FOR TRIESTER OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999062922-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0919562-A1 | PHOSPHONATE NUCLEOTIDE COMPOUNDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5840716-A | ANTIVIRAL AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0832896-A1 | PHOSPHONATE NUCLEOTIDE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-04-01 | — | — | EP | disclosed |
| EP-0785208-A1 | Phosphonate nucleotide compounds | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996033201-A1 | ACYCLOVIR DERIVATIVES AS ANTIVIRAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1996-10-24 | — | — | WO | disclosed |