Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727818 | 0.91 | GRM2 (0.64) | GRM2 | |
| SCHEMBL6736188 | 0.89 | GRM2 (0.78) | GRM2 | |
| SCHEMBL6732751 | 0.88 | GRM2 (0.73) | GRM2NR3C1 | |
| SCHEMBL6733179 | 0.88 | GRM2 (0.61) | GRM2NR3C1 | |
| SCHEMBL6733345 | 0.87 | GRM2 (0.56) | GRM2NR3C1 | |
| SCHEMBL7419013 | 0.86 | GRM2 (0.55) | GRM2 | |
| SCHEMBL6727779 | 0.85 | GRM2 (0.78) | GRM2 | |
| SCHEMBL6738582 | 0.84 | GRM2 (0.52) | GRM2NR3C1 | |
| SCHEMBL6772754 | 0.83 | GRM2 (0.57) | GRM2 | |
| SCHEMBL5268742 | 0.82 | GRM2 (0.62) | GRM2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006114-A1 | Potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2004-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006114-A1 | Potentiators of glutamate receptors | GRM1, GRIN1, GRM2 | GRM2 3/4885NR3C1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.