SCHEMBL6734643

SCHEMBL6734643

CCNC1CCN(c2ccc(N3CC(CNC(C)=O)OC3=O)cc2F)CC1

nearest known ligand 0.75

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.75
MAOA P21397 5/20 0.75
PTGS1 P23219 2/20 0.75
SDHA P31040 2/20 0.75
LMNA P02545 1/20 0.75
CALML3 P27482 1/20 0.75
F10 P00742 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6734641 1.00 MAOB (0.75) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6495419 0.91 MAOB (0.78) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6988311 0.91 MAOB (0.78) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6988314 0.91 MAOB (0.78) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6986504 0.91 MAOB (0.78) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6984859 0.89 MAOB (0.69) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6984862 0.89 MAOB (0.69) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6995056 0.89 MAOB (0.80) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6191297 0.89 MAOB (0.80) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6995061 0.89 MAOB (0.80) MAOBMAOAPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242591-A1 Oxazolidinone derivatives as pontential antimicrobials RANBAXY LABORATORIES LIMITED (IN) 2004-12-02 US disclosed
EP-1409464-A1 OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS RANBAXY LABORATORIES, LTD. (IN) 2004-04-21 EP disclosed
WO-2003008389-A1 OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2003-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242591-A1 Oxazolidinone derivatives as pontential antimicrobials PDK4, OXA1L, PPARD MAOB 1961/4885MAOA 1955/4885PTGS1 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.