Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740928 | 0.90 | CCR3 (0.75) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| SCHEMBL5854299 | 0.90 | CCR3 (0.75) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6734201 | 0.89 | CCR3 (0.74) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6734198 | 0.89 | CCR3 (0.74) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3936111 | 0.89 | CCR3 (0.74) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3936105 | 0.89 | CCR3 (0.74) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| SCHEMBL5745139 | 0.89 | CCR3 (0.62) | CCR3SMN1; SMN2MEN1KMT2AFAAH | |
| SCHEMBL5745142 | 0.89 | CCR3 (0.62) | CCR3SMN1; SMN2MEN1KMT2AFAAH | |
| SCHEMBL7668454 | 0.87 | CCR3 (0.61) | CCR3SMN1; SMN2MCHR1MEN1KMT2A | |
| SCHEMBL7668452 | 0.87 | CCR3 (0.61) | CCR3SMN1; SMN2MCHR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683074-B1 | PYRROLIDINYL, PIPERAZINYL AND AZEPINYL DERIVATIVES; INFLAMMATORY OR ALLERGIC DISEASES | SYNTEX (U.S.A.) LLC | 2004-01-27 | — | — | US | disclosed |