Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741826 | 0.99 | DPP4 (0.66) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6741912 | 0.93 | DPP4 (0.62) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6741219 | 0.87 | DPP4 (0.60) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL556458 | 0.86 | DPP4 (0.62) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6738715 | 0.86 | DPP4 (0.59) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6739236 | 0.86 | DPP4 (0.59) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL27599942 | 0.85 | DPP4 (0.73) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL554754 | 0.84 | DPP4 (0.76) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6741312 | 0.84 | DPP4 (0.56) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL556236 | 0.84 | DPP4 (0.68) | DPP4KMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087587-A1 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087587-A1 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP3, DPP7 | DPP4 1/4885KMT2A 3433/4885ALDH1A1 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.