SCHEMBL6738345

SCHEMBL6738345

CCCCOC(Cc1ccc(OCCCC=C2c3ccccc3-c3ccccc32)cc1)C(=O)OCC

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 16/20 0.57
PPARA Q07869 14/20 0.57
PPARD Q03181 10/20 0.47
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6731650 0.98 PPARG (0.55) PPARGPPARAPPARDTDP1
SCHEMBL6731670 0.97 PPARG (0.54) PPARGPPARAPPARD
SCHEMBL6738750 0.97 PPARG (0.54) PPARGPPARAPPARD
SCHEMBL6735864 0.97 PPARG (0.60) PPARGPPARAPPARDTDP1
SCHEMBL6735814 0.96 PPARG (0.57) PPARGPPARAPPARDTDP1
SCHEMBL6739254 0.95 PPARG (0.58) PPARGPPARAPPARDTDP1
SCHEMBL6741589 0.94 PPARG (0.57) PPARGPPARAPPARD
SCHEMBL6731236 0.94 PPARG (0.57) PPARGPPARAPPARD
SCHEMBL6737545 0.94 PPARG (0.65) PPARGPPARAPPARD
SCHEMBL7774106 0.92 PPARG (0.55) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6683111-B2 SUCH AS 2-ETHOXY-3-(4-(2-XANTHEN-9-YLIDENE-ETHOXY)-PHENYL)-PROPIONIC ACID; FOR TREATING CONDITIONS ASSOCIATED WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; TREATMENT OF DIABETES/OBESITY NOVO NORDISK A/S (DK) 2004-01-27 US claimed
US-20020115654-A1 New compounds, their preparation and use JEPPESEN LONE (DK) 2002-08-22 US claimed
EP-1123267-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP claimed
WO-2000023415-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO claimed
US-6683111-B2 SUCH AS 2-ETHOXY-3-(4-(2-XANTHEN-9-YLIDENE-ETHOXY)-PHENYL)-PROPIONIC ACID; FOR TREATING CONDITIONS ASSOCIATED WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; TREATMENT OF DIABETES/OBESITY NOVO NORDISK A/S (DK) 2004-01-27 US disclosed
US-20020115654-A1 New compounds, their preparation and use JEPPESEN LONE (DK) 2002-08-22 US disclosed
US-6353018-B1 Compounds, their preparation and use NOVO NORDISK A/S (DK) 2002-03-05 US disclosed
EP-1123267-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP disclosed
WO-2000023415-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115654-A1 New compounds, their preparation and use PPARG, PPARD, PPARA PPARG 1/4885PPARA 3/4885PPARD 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.