SCHEMBL673875

SCHEMBL673875

CCC(CCCCCc1c(C)ccc(O)c1-n1nc2ccccc2n1)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921992 0.78 NPC1 (0.41) NPC1LMNARAB9AMAPT
SCHEMBL1921750 0.78 NPC1 (0.41) NPC1LMNARAB9AMAPT
SCHEMBL31361781 0.72 NPC1 (0.36) NPC1LMNARAB9AMAPT
SCHEMBL26621812 0.71 NR1H3 (0.41) NPC1LMNARAB9A
SCHEMBL30801194 0.70 NR1H2 (0.47) NPC1RAB9A
SCHEMBL30678693 0.70 NR1H2 (0.47) NPC1RAB9A
SCHEMBL6744460 0.69 DPP4 (0.43) NPC1LMNARAB9A
SCHEMBL15537671 0.68 TNF (0.46) NPC1LMNARAB9ASMN1; SMN2MAPT
SCHEMBL14479254 0.68 TDP1 (0.44) LMNA
SCHEMBL673476 0.67 NPC1 (0.38) NPC1LMNARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024038853-A1 RESIN COMPOSITION, PELLETS, AND MOLDED ARTICLE 三菱ケミカル株式会社 2024-02-22 WO disclosed
WO-2023214487-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION 三菱ケミカル株式会社 2023-11-09 WO disclosed
US-7968632-B2 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-06-28 US disclosed
EP-1892266-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES MITSUBISHI ENG PLASTICS CORP (JP) 2010-07-21 EP disclosed
US-20090186967-A1 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) 2009-07-23 US disclosed
EP-1892266-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES Mitsubishi Engineering-Plastics Corporation (JP) 2008-02-27 EP disclosed
US-6762250-B2 TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-07-13 US disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
US-20040054116-A1 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-03-18 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed