Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 4/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741177 | 0.84 | POLB (0.43) | POLBCLCN2TSHRCYP3A4HSD17B10 | |
| SCHEMBL17829704 | 0.83 | POLB (0.41) | POLBTSHRCYP3A4HSD17B10PKMYT1 | |
| SCHEMBL27432701 | 0.79 | CYP3A4 (0.34) | CLCN2TSHRCYP3A4HSD17B10MAPT | |
| SCHEMBL6742562 | 0.79 | GUSB (0.45) | TSHRCYP3A4HSD17B10KMT2AMAPT | |
| SCHEMBL27679701 | 0.78 | POLB (0.42) | POLBCLCN2TSHRHSD17B10PKMYT1 | |
| SCHEMBL31307651 | 0.78 | POLB (0.48) | POLBTSHRCYP3A4HSD17B10PKMYT1 | |
| SCHEMBL4640149 | 0.78 | CLCN2 (0.47) | POLBCLCN2TSHRCYP3A4HSD17B10 | |
| SCHEMBL28060147 | 0.78 | PKMYT1 (0.42) | POLBTSHRHSD17B10PKMYT1CDK1 | |
| SCHEMBL17825685 | 0.76 | POLB (0.36) | POLBPKMYT1KMT2AKDRLIMK1 | |
| SCHEMBL3823076 | 0.74 | POLB (0.42) | POLBCLCN2TSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683213-B1 | CHEMICAL INTERMEDIATES FOR PYRIDINEDICARBOXAMIDE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |
| EP-1165496-B1 | SUBSTITUTED ANILINE COMPOUNDS | BASF AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
| CN-1345304-A | Substituted aniline compounds | BASF AG (DE) | 2002-04-17 | — | — | CN | disclosed |
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| EP-1165496-A1 | SUBSTITUTED ANILINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059868-A1 | SUBSTITUTED ANILINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |