Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 1.00 |
| ▸ | RARB | P10826 | 14/20 | 1.00 |
| ▸ | RARA | P10276 | 11/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357613 | 1.00 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL5084167 | 0.88 | RARG (0.79) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL6371423 | 0.88 | RARG (0.79) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL6535556 | 0.87 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL30012262 | 0.87 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8765891 | 0.85 | RARB (0.74) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8083653 | 0.85 | RARG (0.88) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL6535711 | 0.85 | RARG (0.83) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL27938212 | 0.84 | RARG (0.81) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL6571308 | 0.83 | RARG (1.00) | RARGRARBRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686386-B1 | COMBATING PHOTOINDUCED OR CHRONOLOGICAL AGEING OF SKIN WITH RETENOIC ACID RECEPTOR AGONIST | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-03 | — | — | US | claimed |
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | claimed |
| EP-0584191-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS. | CIRD GALDERMA (FR) | 1994-03-02 | — | — | EP | claimed |
| WO-1992019583-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | disclosed |
| US-5547983-A | Aromatic and polycyclic compounds and their use in human or veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1996-08-20 | — | — | US | disclosed |
| EP-0584191-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS. | CIRD GALDERMA (FR) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992019583-A1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDECINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-11-12 | — | — | WO | disclosed |