Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 5/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.40 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856444 | 0.84 | GABRR1 (0.43) | SLC1A2SLC1A1GABRR1GABRR2ACE | |
| SCHEMBL4469497 | 0.84 | GABRR1 (0.43) | SLC1A2SLC1A1GABRR1GABRR2ACE | |
| SCHEMBL21708 | 0.84 | GABRR1 (0.53) | SLC1A2SLC1A1GABRR1GABRR2CYP2C9 | |
| SCHEMBL5070654 | 0.81 | GABRR1 (0.46) | SLC1A2SLC1A1GABRR1GABRR2CYP2C9 | |
| SCHEMBL168962 | 0.81 | GABRR1 (0.46) | SLC1A2SLC1A1GABRR1GABRR2CYP2C9 | |
| SCHEMBL4478750 | 0.81 | GABRR1 (0.46) | SLC1A2SLC1A1GABRR1GABRR2CYP2C9 | |
| SCHEMBL20656751 | 0.80 | GABRR1 (0.40) | SLC1A2SLC1A1GABRR1GABRR2LMNA | |
| SCHEMBL169047 | 0.78 | GABRR1 (0.44) | SLC1A2SLC1A1GABRR1GABRR2ACE | |
| SCHEMBL21641650 | 0.78 | GABRR1 (0.44) | SLC1A2SLC1A1GABRR1GABRR2ACE | |
| SCHEMBL5525138 | 0.75 | PEPD (0.48) | ACELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023369-B | Process for preparing TDI based polyurethane flexible foams containing organic acid anhydrides and/or organic acid chlorides | 科思创德国股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20200079895-A1 | METHOD FOR PRODUCING TDI-BASED FLEXIBLE POLYURETHANE FOAMS CONTAINING ORGANIC ACID ANHYDRIDES AND/OR ORGANIC ACID CHLORIDES | COVESTRO DEUTSCHLAND AG (DE) | 2020-03-12 | — | — | US | disclosed |
| EP-3548534-A1 | METHOD FOR PRODUCING TDI-BASED FLEXIBLE POLYURETHANE FOAMS CONTAINING ORGANIC ACID ANHYDRIDES AND/OR ORGANIC ACID CHLORIDES | Covestro Deutschland AG (DE) | 2019-10-09 | — | — | EP | disclosed |
| US-20040209969-A1 | Polyisocyanate polyaddition products | ARLT ANDREAS | 2004-10-21 | — | — | US | disclosed |
| US-6800667-B1 | CATALYTIC CONDENSATION POLYMERIZATION OF POLYURETHANE FOAM USING ORGANIC AMINE OR METAL COMPOUND IN PRESENCE OF UNREACTED ACID ANHYDRIDE; MATTRESSES, UPHOLSTERY, OR CARPETS | BASF CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-6794421-B2 | comprising hydrophobic compounds plus at least one further compound and/or derivative thereof reactive toward primary amines, compound being selected from cyclic sulfonic esters and sulfones and mixtures thereof | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | disclosed |
| US-20030130366-A1 | Polyisocyanate polyaddition products | ARLT ANDREAS (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6495611-B1 | MATTRESS OR FURNITURE UPHOLSTERY OR CARPET BACKING COMPRISING A FLEXIBLE POLYURETHANE FOAM COMPRISING HYDROPHOBIC COMPOUNDS PLUS AT LEAST ONE CYCLODEXTRIN, RESORCINARENE, CYCLOPHANE AND/OR CYCLOCALIXARENE | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |