SCHEMBL67399

SCHEMBL67399

C=C1[CH]C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1403442 0.67
SCHEMBL2407064 0.65
SCHEMBL11331916 0.60
SCHEMBL11152394 0.60
SCHEMBL22296900 0.60
SCHEMBL6701485 0.58
SCHEMBL129646 0.47
SCHEMBL10545264 0.47
SCHEMBL6765508 0.47
SCHEMBL239887 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 840 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4389745-A1 PYRIDONE COMPOUND HAVING INTEGRASE INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2024-06-26 EP claimed
CN-118201930-A WEE1 protein kinase degradation agent and application thereof 杭州格博生物医药有限公司 2024-06-14 CN claimed
EP-4375277-A1 LPA1 SMALL MOLECULE ANTAGONIST Tuojie Biotech (Shanghai) Co., Ltd. (CN) 2024-05-29 EP claimed
WO-2024088296-A1 PIPERIDINOPYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 上海拓界生物医药科技有限公司 2024-05-02 WO claimed
CN-117886814-A PD-1/PD-L1 small molecule inhibitor and application thereof in medicines 广东东阳光药业股份有限公司 2024-04-16 CN claimed
CN-117715908-A Pyridone compounds having integrase inhibitory activity and their pharmaceutical use 江苏恒瑞医药股份有限公司 2024-03-15 CN claimed
WO-2024027814-A1 COMPOUND HAVING KRAS G12D INHIBITORY EFFECT 杭州中美华东制药有限公司 2024-02-08 WO claimed
CN-117460721-A LPA1 small molecule antagonist 上海拓界生物医药科技有限公司 2024-01-26 CN claimed
WO-2023141593-A2 PROCESS FOR SYNTHESIS OF GALBULIMIMA ALKALOID 18 AND COMPOUNDS USEFUL AS OPIOID RECEPTOR ANTAGONISTS AND AGONISTS THE SCRIPPS RESEARCH INSTITUTE (US) 2023-07-27 WO claimed
WO-2023115167-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 WO claimed
WO-1997042174-A1 SUBSTITUTED INDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS PHOSPHODIESTERASE (PDE) TYPE IV AND THE PRODUCTION OF TUMOR NECROSIS FACTOR (TNF) PFIZER INC. (US) 1997-11-13 WO claimed
US-5596013-A INHIBITORS OF PHOSPHODIESTERASE TYPE IV AND PRODUCTION OF TUMOR NECROSIS FACTOR PFIZER INC (US) 1997-01-21 US claimed
EP-0738270-A1 DIHYDRO PYRAZOLOPYRROLES PFIZER INC. (US) 1996-10-23 EP claimed
US-5543406-A TREATING ANDROGEN RESPONSIVE OR MEDIATED DISEASE GLAXO WELLCOME, INC. (US) 1996-08-06 US claimed
US-5508300-A INHIBIT PHOSPHODIESTERASE AND PRODUCTION OF TUMOR NECROSIS FACTOR; TREATING INFLAMMATORY DISEASES PFIZER INC. (US) 1996-04-16 US claimed
EP-0674651-A1 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1995-10-04 EP claimed
WO-1995019362-A1 DIHYDRO PYRAZOLOPYRROLES PFIZER INC. (US) 1995-07-20 WO claimed
EP-0641356-A1 INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE GLAXO WELLCOME INC. (US) 1995-03-08 EP claimed
WO-1994014833-A2 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1994-07-07 WO claimed
WO-1993013124-A1 INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE GLAXO INC. (US) 1993-07-08 WO claimed