Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.45 |
| ▸ | FYN | P06241 | 4/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224900 | 0.93 | SRC (0.49) | SRCFYNMELKEGFRMAP2K1 | |
| SCHEMBL3222029 | 0.82 | SRC (0.46) | SRCFYNMELKEGFRMAP2K1 | |
| SCHEMBL3221456 | 0.82 | SRC (0.47) | SRCFYNMELKEGFRMAP2K1 | |
| SCHEMBL3222427 | 0.80 | SRC (0.47) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3229968 | 0.80 | SRC (0.49) | SRCFYNEGFRMAP2K1ABL1 | |
| SCHEMBL3228093 | 0.80 | SRC (0.70) | SRCFYNEGFRMAP2K1ABL1 | |
| SCHEMBL3229093 | 0.79 | SRC (0.46) | SRCFYNEGFRMAP2K1ABL1 | |
| SCHEMBL3222335 | 0.79 | MAP2K1 (0.48) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3221346 | 0.78 | EGFR (0.52) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3223162 | 0.78 | SRC (0.58) | SRCFYNEGFRMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689772-B1 | ANTINEOPLASTIC AGENTS; OSTEOPOROSIS; POLYCYSTIC KIDNEY DISEASE; ANTIVIRAL AGENTS | WYETH | 2004-02-10 | — | — | US | disclosed |