Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.77 |
| ▸ | PPARA | Q07869 | 13/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739343 | 0.96 | PPARG (0.70) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6736565 | 0.95 | PPARG (0.69) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6732164 | 0.95 | PPARA (0.85) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6737918 | 0.91 | PPARG (0.76) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6741477 | 0.91 | PPARA (0.88) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6736281 | 0.90 | PPARG (0.78) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6741537 | 0.90 | PPARG (0.77) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6735406 | 0.87 | PPARG (0.81) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6740647 | 0.87 | PPARG (0.70) | PPARGPPARAKDM4EALDH1A1NPSR1 | |
| SCHEMBL6734833 | 0.87 | PPARA (1.00) | PPARGPPARAKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115654-A1 | New compounds, their preparation and use | JEPPESEN LONE (DK) | 2002-08-22 | — | — | US | claimed |
| US-6683111-B2 | SUCH AS 2-ETHOXY-3-(4-(2-XANTHEN-9-YLIDENE-ETHOXY)-PHENYL)-PROPIONIC ACID; FOR TREATING CONDITIONS ASSOCIATED WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; TREATMENT OF DIABETES/OBESITY | NOVO NORDISK A/S (DK) | 2004-01-27 | — | — | US | disclosed |
| US-20020115654-A1 | New compounds, their preparation and use | JEPPESEN LONE (DK) | 2002-08-22 | — | — | US | disclosed |
| US-6353018-B1 | Compounds, their preparation and use | NOVO NORDISK A/S (DK) | 2002-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115654-A1 | New compounds, their preparation and use | PPARG, PPARD, PPARA | PPARG 1/4885PPARA 3/4885KDM4E 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.