Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516022 | 0.81 | ESR2 (0.52) | — | |
| SCHEMBL9372709 | 0.80 | GAA (0.41) | SLC18A3SIGMAR1SRD5A1GAAMAPT | |
| SCHEMBL17440329 | 0.76 | SLC18A3 (0.41) | SLC18A3SIGMAR1SRD5A1GAAMAPT | |
| SCHEMBL9876026 | 0.76 | SRD5A1 (0.43) | SLC18A3SIGMAR1SRD5A1LMNATSHR | |
| SCHEMBL25073357 | 0.76 | SLC18A3 (0.41) | SLC18A3SIGMAR1SRD5A1GAAMAPT | |
| SCHEMBL24105190 | 0.76 | SLC18A3 (0.41) | SLC18A3SIGMAR1SRD5A1GRIN2BADRA1A | |
| SCHEMBL17440328 | 0.76 | SLC18A3 (0.41) | SLC18A3SIGMAR1SRD5A1GAAMAPT | |
| SCHEMBL14789289 | 0.76 | SLC18A3 (0.37) | SLC18A3SIGMAR1SRD5A1GAAMAPT | |
| SCHEMBL28813917 | 0.74 | SLC18A3 (0.52) | SLC18A3SIGMAR1SRD5A1GRIN2BADRA1A | |
| SCHEMBL19867003 | 0.72 | SRD5A1 (0.32) | SLC18A3SIGMAR1SRD5A1ADRA1ADAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686509-B2 | Process for producing α, α-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030078460-A1 | Process for producing alpha, alpha-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2003-04-24 | — | — | US | disclosed |