Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.81 |
| ▸ | FYN | P06241 | 3/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.68 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222282 | 0.90 | SRC (1.00) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3224206 | 0.85 | SRC (1.00) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3222680 | 0.83 | SRC (1.00) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3224481 | 0.83 | SRC (1.00) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL7174603 | 0.82 | SRC (0.85) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3229384 | 0.82 | SRC (0.89) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3227471 | 0.81 | SRC (1.00) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3220031 | 0.81 | SRC (0.87) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3222269 | 0.81 | SRC (1.00) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3225828 | 0.81 | SRC (0.89) | SRCFYNEGFRMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689772-B1 | ANTINEOPLASTIC AGENTS; OSTEOPOROSIS; POLYCYSTIC KIDNEY DISEASE; ANTIVIRAL AGENTS | WYETH | 2004-02-10 | — | — | US | disclosed |