Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395874 | 0.86 | FFAR1 (0.47) | MAOBRAB9ANPC1MAOA | |
| SCHEMBL6744828 | 0.80 | MAOB (0.40) | MAOBRAB9ANPC1TP53KMT2A | |
| SCHEMBL6740849 | 0.79 | MAOB (0.47) | MAOBRAB9ANPC1PLAUATM | |
| SCHEMBL5395598 | 0.79 | HPSE (0.48) | RAB9ANPC1TP53SMN1; SMN2 | |
| SCHEMBL5396482 | 0.75 | TYR (0.53) | — | |
| SCHEMBL5396475 | 0.75 | TYR (0.53) | — | |
| SCHEMBL8177216 | 0.73 | HSD17B10 (0.50) | MAOBRAB9ANPC1LMNAKMT2A | |
| SCHEMBL5827815 | 0.72 | KMT2A (0.52) | RAB9ANPC1ATMKMT2AL3MBTL1 | |
| SCHEMBL28184488 | 0.70 | NPC1 (0.56) | RAB9ANPC1ATMKMT2AL3MBTL1 | |
| SCHEMBL11619290 | 0.68 | CYP1A2 (0.46) | LMNATP53KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693098-B2 | CARBOXYLIC ACID OR TETRAZOLE DERIVATIVES CONTAINING CARBAMATE GROUPS ARE USEFUL FOR TREATING THE CONDITIONS ASSOCIATED WITH THE URINARY TRACT, PAIN, INFLAMMATION, RESPIRATORY STATES, EDEMA FORMATION OF HYPOTENSIVE VASCULAR DISEASES | SYNTEX (U.S.A) LLC | 2004-02-17 | — | — | US | claimed |