Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.57 |
| ▸ | MAOA | P21397 | 8/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741552 | 1.00 | MAOB (0.57) | MAOBMAOACES2ACHE | |
| SCHEMBL6738033 | 1.00 | MAOB (0.57) | MAOBMAOACES2ACHE | |
| SCHEMBL6742536 | 0.94 | MAOB (0.56) | MAOBMAOACES2 | |
| SCHEMBL6744180 | 0.94 | MAOB (0.56) | MAOBMAOACES2 | |
| SCHEMBL17641334 | 0.85 | MAOB (0.46) | MAOBMAOACES2 | |
| SCHEMBL29000513 | 0.85 | MAOB (0.43) | MAOBMAOAACHE | |
| SCHEMBL17763438 | 0.82 | MAOB (0.61) | MAOBMAOACES2ACHE | |
| SCHEMBL7879427 | 0.82 | MAOB (0.68) | MAOBMAOACES2ACHE | |
| SCHEMBL29693411 | 0.82 | MAOB (0.68) | MAOBMAOACES2ACHE | |
| SCHEMBL30786049 | 0.82 | MAOB (0.61) | MAOBMAOACES2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689808-B2 | TREATING OR PREVENTING EPILEPSY OR NEURODEGENERATIVE DISEASES | LES LABORATOIRES SERVIER (FR) | 2004-02-10 | — | — | US | disclosed |
| US-20030220393-A1 | Substituted phthalides, a process for their preparations and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2003-11-27 | — | — | US | disclosed |
| EP-1320528-A2 | SUBSTITUTED PHTHALIDES AS ANTI-CONVULSIVE DRUGS | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002000638-A2 | SUBSTITUTED PHTHALIDES AS ANTI-CONVULSIVE DRUGS | INSTITUTE OF MATERIA MEDICA (CN) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220393-A1 | Substituted phthalides, a process for their preparations and pharmaceutical compositions containing them | NR5A2, NR2E3, NR4A1 | MAOB 1112/4885MAOA 572/4885CES2 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.