Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HLCS | P50747 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076491 | 0.98 | TP53 (0.47) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL10959669 | 0.94 | CYP1A2 (0.44) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL7167062 | 0.94 | CYP1A2 (0.44) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL11861937 | 0.91 | CYP1A2 (0.48) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL10704088 | 0.91 | CYP1A2 (0.48) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL1036088 | 0.89 | CYP1A2 (0.46) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL5259007 | 0.82 | TP53 (0.47) | TP53CYP1A2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8393094 | 0.82 | TP53 (0.39) | TP53CYP1A2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL28102875 | 0.82 | TP53 (0.40) | TP53CYP1A2ALDH1A1HPGDALOX15 | |
| SCHEMBL28050847 | 0.82 | TP53 (0.40) | TP53CYP1A2ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2015058-A | — | — | None | — | — | JP | disclosed |
| JP-2004137228-A | METHOD FOR PRODUCING 2-SUBSTITUTED-4-OXO-4, 5, 6, 7-TETRAHYDROINDOLE COMPOUND | NIPPON ZEON CO LTD | 2004-05-13 | — | — | JP | disclosed |
| JP-H0215058-A | PRODUCTION OF 2-SUBSTITUTED-4-OXOTETRAHYDROINDOLES | NIPPON ZEON CO LTD | 1990-01-18 | — | — | JP | disclosed |