Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219544 | 0.84 | SRC (0.68) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL7096102 | 0.84 | SRC (0.56) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL6745108 | 0.81 | SRC (0.67) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL3228995 | 0.76 | SRC (0.51) | SRCFYNEGFRMAP2K1 | |
| SCHEMBL19610615 | 0.76 | SRC (0.48) | SRC | |
| SCHEMBL4904795 | 0.72 | SRC (0.67) | SRC | |
| SCHEMBL19610555 | 0.72 | SRC (0.50) | SRC | |
| SCHEMBL19610512 | 0.71 | SRC (0.52) | SRCEGFR | |
| SCHEMBL19610601 | 0.70 | SRC (0.48) | SRC | |
| SCHEMBL19610534 | 0.70 | SRC (0.45) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689772-B1 | ANTINEOPLASTIC AGENTS; OSTEOPOROSIS; POLYCYSTIC KIDNEY DISEASE; ANTIVIRAL AGENTS | WYETH | 2004-02-10 | — | — | US | disclosed |