Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.57 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490770 | 0.82 | GRIK1 (0.59) | GRIK1GRIK2CES2CES1 | |
| SCHEMBL6574705 | 0.82 | GRIK1 (0.59) | GRIK1GRIK2CES2CES1 | |
| SCHEMBL1088357 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2 | |
| SCHEMBL157326 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2 | |
| SCHEMBL564180 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2CES2CES1 | |
| SCHEMBL1651116 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2 | |
| SCHEMBL165975 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2 | |
| SCHEMBL4732941 | 0.80 | GRIK1 (0.62) | GRIK1GRIK2 | |
| SCHEMBL3853225 | 0.78 | GRIK1 (0.56) | GRIK1GRIK2 | |
| SCHEMBL563481 | 0.78 | GRIK1 (0.56) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6695880-B1 | Intraocular lenses and methods for their manufacture | JOHNSON & JOHNSON VISION CARE, INC. | 2004-02-24 | — | — | US | disclosed |
| EP-1333775-A2 | INTRAOCULAR LENSES AND METHODS FOR THEIR MANUFACTURE | Johnson & Johnson Vision Care, Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002034158-A2 | INTRAOCULAR LENSES AND METHODS FOR THEIR MANUFACTURE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2002-05-02 | — | — | WO | disclosed |