Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818149 | 0.87 | MC4R (0.46) | MC4RKCNH2NISCH | |
| SCHEMBL4824056 | 0.85 | MC4R (0.44) | MC4RKCNH2NISCH | |
| SCHEMBL4064122 | 0.85 | MC4R (0.56) | MC4RKCNH2NISCH | |
| SCHEMBL4362042 | 0.85 | MC4R (0.52) | MC4RKCNH2 | |
| SCHEMBL4147932 | 0.81 | MC4R (0.53) | MC4RKCNH2 | |
| SCHEMBL4364683 | 0.81 | MC4R (0.49) | MC4RKCNH2NISCHPTGDR2 | |
| SCHEMBL4367598 | 0.80 | MC4R (0.54) | MC4RKCNH2 | |
| SCHEMBL4540122 | 0.79 | MC4R (0.46) | MC4RKCNH2 | |
| SCHEMBL4008428 | 0.79 | MC4R (0.63) | MC4RKCNH2NISCH | |
| SCHEMBL4364676 | 0.78 | MC4R (0.65) | MC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |