Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | NEK1 | Q96PY6 | 4/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13092872 | 0.81 | CYP17A1 (0.52) | CYP17A1GRIA4CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL3465616 | 0.79 | — | — | |
| SCHEMBL3465286 | 0.79 | — | — | |
| SCHEMBL9325791 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL9433725 | 0.77 | SLC6A4 (0.42) | CYP17A1SLC6A4KCNH2 | |
| SCHEMBL28053566 | 0.76 | CYP17A1 (0.45) | CYP17A1GRIA4CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL23092069 | 0.76 | SLC6A4 (0.70) | SLC6A4NEK1 | |
| SCHEMBL5878351 | 0.75 | GRIA4 (0.57) | CYP17A1GRIA4CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL12545246 | 0.75 | CYP17A1 (0.53) | CYP17A1GRIA4CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL11296454 | 0.75 | SLC6A4 (0.53) | CYP17A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054009-A1 | (BIS)sulfonamide derivatives | KNOBELSDORF JAMES ALLEN (US) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054009-A1 | (BIS)sulfonamide derivatives | GRIN2A, GRIN2B, GABRE | CYP17A1 1630/4885GRIA4 14/4885SLC6A4 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.