⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632545 | 1.00 | — | — | |
| SCHEMBL9492628 | 0.75 | — | — | |
| SCHEMBL5634598 | 0.75 | — | — | |
| SCHEMBL5958320 | 0.71 | — | — | |
| SCHEMBL20339129 | 0.71 | — | — | |
| SCHEMBL6593099 | 0.71 | — | — | |
| SCHEMBL17907452 | 0.67 | — | — | |
| SCHEMBL28271742 | 0.67 | — | — | |
| SCHEMBL8747799 | 0.64 | — | — | |
| SCHEMBL10359813 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703388-B2 | DIBENZODIAZEPINE DERIVATIVES; ANTIHISTAMINES, LEUKOTRIENE INHIBITORS, ANTIALLERGENS, ANTIASTHMATICS; HAY FEVER, ATOPIC DERMATITIS, AND URTICARIA TREATMENT | EISAI CO., LTD. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20030171367-A1 | Nitrogen-containing tricyclic compounds and drugs containing the same | EISAI CO., LTD. | 2003-09-11 | — | — | US | disclosed |
| US-6489336-B2 | PHENOTHIAZINE, ACRIDAN, ACRIDONE OXIME, ACRIDONE HYDRAZONE, OR DIBENZODIAZEPINE DERIVATIVES; TYROSINE KINASE INHIBITORS; TREATING ALLERGIC DISEASES | EISAI CO., LTD. (JP) | 2002-12-03 | — | — | US | disclosed |
| US-20020103189-A1 | Nitrogen-containing tricyclic compounds and drugs containing the same | EISAI CO., LTD. | 2002-08-01 | — | — | US | disclosed |
| US-6333322-B1 | FOR THERAPY OF ASTHMA, ALLERGIC RHINITIS, ATOPIC DERMATITIS, URTICARIA, HAY FEVER, GASTROINTESTINAL ALLERGY AND FOOD ALLERGY | EISAI CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-0889037-A1 | NITROGENOUS TRICYCLIC COMPOUNDS AND DRUGS COMPRISING THE SAME | Eisai Co., Ltd. (JP) | 1999-01-07 | — | — | EP | disclosed |
| EP-0857721-A1 | ACRIDONE COMPOUNDS | Eisai Co., Ltd. (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0433883-B1 | PROCESS FOR THE PREPARATION OF ALPHA-FORMYLAMINONITRILES | BASF Aktiengesellschaft (DE) | 1993-03-24 | — | — | EP | disclosed |
| EP-0433884-B1 | PROCESS FOR THE PREPARATION OF ALPHA-FORMYLAMINONITRILES | BASF Aktiengesellschaft (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0433884-A1 | Process for the preparation of alpha-formylaminonitriles | BASF Aktiengesellschaft (DE) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433883-A1 | Process for the preparation of alpha-formylaminonitriles | BASF Aktiengesellschaft (DE) | 1991-06-26 | — | — | EP | disclosed |