Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 17/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL5448361 | 0.94 | MEN1 (0.51) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL294456 | 0.87 | MAPK1 (0.52) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL3954172 | 0.87 | MEN1 (0.52) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL4799143 | 0.84 | MAPK1 (0.55) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL5446268 | 0.83 | MAPK1 (0.58) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Di(Hydroxyethyl)Ether SCHEMBL6293502 | 0.83 | MEN1 (0.73) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Sulfuric Acid SCHEMBL2993814 | 0.83 | MEN1 (0.67) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL932213 | 0.83 | MEN1 (0.52) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL17419075 | 0.82 | MEN1 (0.52) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL17418396 | 0.82 | MEN1 (0.52) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214108-A1 | Ionic liquids as dissolution inhibitors in imageable elements | KODAK POLYCHROME GRAPHICS LLC | 2004-10-28 | — | — | US | disclosed |