Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600672 | 0.82 | SLC22A6 (0.46) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL16600086 | 0.78 | SLC22A6 (0.42) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL8741702 | 0.76 | TDP1 (0.56) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL420866 | 0.74 | — | — | |
| SCHEMBL10054699 | 0.74 | — | — | |
| SCHEMBL3811161 | 0.74 | — | — | |
| SCHEMBL7451358 | 0.73 | FOLH1 (0.43) | SLC22A6SMN1; SMN2FOLH1TET2KDM4A | |
| SCHEMBL16600326 | 0.72 | TET2 (0.50) | LMNAFOLH1GPR84TET2KDM4A | |
| SCHEMBL17867252 | 0.71 | SLC22A6 (0.40) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 | |
| SCHEMBL692357 | 0.70 | SLC22A6 (0.43) | SLC22A6SMN1; SMN2GABRR1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693222-B2 | HYDRATING ACROLEIN USING ACID CATALYST, CATALYTICALLY HYDROGENATING PRODUCT, REFINING MIXTURE CONTAINING WATER, 1,3-PROPANEDIOL AND HIGH BOILING BY-PRODUCTS, TREATING BOILER SUMP IN AQUEOUS SOLUTION WITH ACID CATALYST, NEUTRALIZING | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-02-17 | — | — | US | disclosed |