⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3770046 | 0.83 | PIP5K1C (0.30) | — | |
| SCHEMBL8029968 | 0.82 | — | — | |
| SCHEMBL19573892 | 0.79 | — | — | |
| SCHEMBL22448448 | 0.79 | — | — | |
| SCHEMBL19573890 | 0.79 | — | — | |
| SCHEMBL10076693 | 0.79 | — | — | |
| SCHEMBL5084320 | 0.79 | — | — | |
| SCHEMBL8150730 | 0.79 | — | — | |
| SCHEMBL4157344 | 0.76 | — | — | |
| SCHEMBL7952337 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | claimed |
| US-20230312506-A1 | PROCESS | GIVAUDAN SA (CH) | 2023-10-05 | — | — | US | claimed |
| EP-4204407-A1 | PROCESS | Givaudan SA (CH) | 2023-07-05 | — | — | EP | claimed |
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | disclosed |
| US-20240139087-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | GIVAUDAN SA (CH) | 2024-05-02 | — | — | US | disclosed |
| US-20240132487-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | GIVAUDAN SA (CH) | 2024-04-25 | — | — | US | disclosed |
| EP-4291553-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | Givaudan SA (CH) | 2023-12-20 | — | — | EP | disclosed |
| CN-116867775-A | Organic compounds as TRPM8 activators | 奇华顿股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20230312506-A1 | PROCESS | GIVAUDAN SA (CH) | 2023-10-05 | — | — | US | disclosed |
| EP-4204407-A1 | PROCESS | Givaudan SA (CH) | 2023-07-05 | — | — | EP | disclosed |
| CN-116209659-A | Method | 奇华顿股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2010014943-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| US-20100003246-A1 | Novel heterocyclic compounds and uses therof | NOVARTIS AG (CH) | 2010-01-07 | — | — | US | disclosed |
| US-20090263483-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC | 2009-10-22 | — | — | US | disclosed |
| WO-2009126938-A1 | NANOPARTICLE FORMULATIONS AND USES THEREOF | ABRAXIS BIOSCIENCES, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126401-A1 | COMPOSITIONS OF HYDROPHOBIC TAXANE DERIVATIVES AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126175-A1 | COMPOSITIONS OF HYDROPHOBIC TAXANE DERIVATIVES AND USES THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009115572-A2 | NOVEL HETEROCYCLIC COMPOUNDS AND USES THEROF | NOVARTIS AG (CH) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009042694-A1 | (3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING | COMENTIS, INC. (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008155727-A1 | PLATINUM (IV) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2008-12-24 | — | — | WO | disclosed |