Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 13/20 | 0.46 |
| ▸ | CDK2 | P24941 | 12/20 | 0.46 |
| ▸ | CDK1 | P06493 | 11/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.46 |
| ▸ | CDK9 | P50750 | 5/20 | 0.46 |
| ▸ | CDK7 | P50613 | 4/20 | 0.46 |
| ▸ | CCNK | O75909 | 4/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753118 | 0.81 | CDK1 (0.46) | CDK5CDK2CDK1CCNE1DYRK1A | |
| SCHEMBL23993147 | 0.73 | CDK2 (0.58) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL5335413 | 0.68 | TDP1 (0.67) | CDK5CDK2CDK1CCNE1DYRK1A | |
| SCHEMBL34470227 | 0.68 | CDK1 (0.70) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL19111944 | 0.68 | CDK1 (0.67) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL29684386 | 0.68 | CDK1 (0.67) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL19112165 | 0.68 | CDK1 (0.70) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL23752348 | 0.68 | CDK1 (0.67) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL19112159 | 0.68 | CDK1 (0.70) | CDK5CDK2CDK1CCNA2CCNA1 | |
| SCHEMBL30356164 | 0.68 | CDK1 (0.70) | CDK5CDK2CDK1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703395-B2 | ADMINISTERING2-(((3-HYDROXYPROPYL)AMINO)-6-BENZYLAMINO)-9 -ISOPROPYLPURINE OR ITS SALT FOR THERAPY OF LEUKEMIA | INSTITUTE OF EXPERIMENTAL BOTANY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2004-03-09 | — | — | US | claimed |