Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | HTR3A | P46098 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SCN1A | P35498 | 4/20 | 0.65 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.65 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL11583887 | 0.90 | TSHR (0.67) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL11584964 | 0.89 | TSHR (0.70) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL11581724 | 0.88 | TSHR (0.65) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL6743572 | 0.87 | SCN1A (0.68) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL3381482 | 0.85 | HRH3 (0.68) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL3380743 | 0.85 | TSHR (0.68) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL21705606 | 0.84 | TSHR (0.72) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL28853482 | 0.83 | CYP2D6 (0.74) | TSHRCYP2D6HRH3MAOAHTR3A | |
| SCHEMBL8489298 | 0.83 | TSHR (0.74) | TSHRCYP2D6HRH3MAOAHTR3A | |
| Methylene Chloride SCHEMBL11582056 | 0.82 | HRH3 (0.65) | TSHRCYP2D6HRH3MAOAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214867-A1 | Quaternary salts of n-substituted cyclic or acyclic amines as pharmaceuticals | UCB FARCHIM S.A. (CH) | 2004-10-28 | — | — | US | disclosed |
| EP-1278736-A1 | QUATERNARY SALTS OF N-SUBSTITUTED CYCLIC OR ACYCLIC AMINES AS PHARMACEUTICALS | UCB FARCHIM S.A. (CH) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001044218-A1 | QUATERNARY SALTS OF N-SUBSTITUTED CYCLIC OR ACYCLIC AMINES AS PHARMACEUTICALS | UCB FARCHIM S.A. (CH) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214867-A1 | Quaternary salts of n-substituted cyclic or acyclic amines as pharmaceuticals | KCNJ11, NPY1R, NPY5R | TSHR 2985/4885CYP2D6 891/4885HRH3 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.