Phenylthiosemicarbazone

Phenylthiosemicarbazone

SCHEMBL674761

NC(=S)N/N=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.81
POLB P06746 2/20 0.76
MAOB P27338 1/20 0.67
HTT P42858 2/20 0.65
LMNA P02545 2/20 0.65
NPSR1 Q6W5P4 1/20 0.64
MAOA P21397 2/20 0.62
ALDH1A1 P00352 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylthiosemicarbazone SCHEMBL674762 1.00 KDM4E (0.81) KDM4EPOLBMAOBHTTLMNA
Phenylthiosemicarbazone SCHEMBL27878322 0.98 KDM4E (0.78) KDM4EPOLBMAOBHTTLMNA
SCHEMBL28868030 0.90 KDM4E (1.00) KDM4EPOLBMAOBLMNAMAOA
SCHEMBL4262088 0.89 KDM4E (0.76) KDM4EPOLBHTTLMNAMAOA
SCHEMBL14497969 0.89 KDM4E (0.76) KDM4EPOLBHTTLMNAMAOA
SCHEMBL4262083 0.89 KDM4E (0.76) KDM4EPOLBHTTLMNAMAOA
SCHEMBL402672 0.85 KDM4E (0.69) KDM4EHTTLMNAMAOA
SCHEMBL402673 0.85 KDM4E (0.69) KDM4EHTTLMNAMAOA
SCHEMBL13611404 0.85 KDM4E (0.69) KDM4EPOLBHTTLMNAMAOA
SCHEMBL7103895 0.82 KDM4E (0.85) KDM4EPOLBMAOBLMNAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114582813-A Modified alumina ceramic coating diaphragm and preparation method thereof 南通金诺精细陶瓷有限公司 2022-06-03 CN claimed
CN-114437582-A Environment-friendly energy-saving ink cleaning agent and preparation method thereof 南通漫游通艺术包装有限公司 2022-05-06 CN claimed
CN-114262131-A Sludge treatment method 江苏旺佳环保工程设备有限公司 2022-04-01 CN claimed
CN-108047105-B 3-/4-ester-group-substituted benzaldehyde thiosemicarbazone derivative and preparation and application thereof 广东轻工职业技术学院 2020-06-26 CN claimed
CN-107163657-B Radiation-proof composition, paint auxiliary agent and radiation-proof paint 中山市丽莎涂料有限公司 2020-03-27 CN claimed
CN-110511168-A A kind of N- substituent group benzaldehyde thiosemicarbazone analog derivative and its preparation method and application UNIV NORTHWESTERN 2019-11-29 CN claimed
CN-106818767-B A kind of composition pesticide and its preparation and application 山东农业大学 2019-11-22 CN claimed
CN-108129522-A Phthalocyanine connects aryl ruthenium compound and application thereof and preparation method 广西师范学院 2018-06-08 CN claimed
CN-108047105-A 3-/4- ester group substituted benzaldehyde thiosemicarbazone derivatives and its preparation and application 广东轻工职业技术学院 2018-05-18 CN claimed
CN-107163657-A A kind of radiation-preventing composition and a kind of coating additive and radiation shielding coating 中山市丽莎涂料有限公司 2017-09-15 CN claimed
EP-3006496-B1 TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR BRIDGESTONE CORP (JP) 2017-07-19 EP claimed
CN-106818767-A A kind of composition pesticide and its preparation and application 山东农业大学 2017-06-13 CN claimed
CN-102964387-B Organic metal ruthenium ion pair compound and preparation method and application thereof UNIV GUANGXI TEACHERS EDUCATION 2015-01-21 CN claimed
CN-103709083-A Benzaldehyde thiosemicarbazone derivative and application UNIV GUILIN TECH GUT 2014-04-09 CN claimed
CN-102964387-A Organic metal ruthenium ion pair compound and preparation method and application thereof UNIV GUANGXI TEACHERS EDUCATION 2013-03-13 CN claimed
WO-2007051249-A1 SEED DRESSING A & C CHEMICALS PTY LTD (AU) 2007-05-10 WO claimed
CN-121405595-A Use of benzaldehyde thiosemicarbazone compound and bactericide 华中师范大学 2026-01-27 CN disclosed
CN-121405595-A Use of benzaldehyde thiosemicarbazone compound and bactericide 华中师范大学 2026-01-27 CN disclosed
US-4199413-A TIN SALT LAYER GIVES HIGH DENSITY IMAGES MITA INDUSTRIAL COMPANY LIMITED (JP) 1980-04-22 US disclosed
US-4035244-A Electric recording process MITA INDUSTRIAL COMPANY LIMITED (JA) 1977-07-12 US disclosed