⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634012 | 0.80 | TP53 (0.30) | — | |
| SCHEMBL6744443 | 0.78 | — | — | |
| SCHEMBL10860471 | 0.75 | — | — | |
| SCHEMBL14184226 | 0.75 | TP53 (0.33) | — | |
| SCHEMBL5268352 | 0.73 | — | — | |
| SCHEMBL6744848 | 0.73 | CYP2C19 (0.31) | — | |
| SCHEMBL486485 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL16504197 | 0.71 | — | — | |
| SCHEMBL5850456 | 0.69 | — | — | |
| SCHEMBL11572837 | 0.69 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459766-A | Fluorosilicone oil containing phosphate and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-08-09 | — | — | CN | claimed |
| CN-118459766-A | Fluorosilicone oil containing phosphate and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-08-09 | — | — | CN | disclosed |
| CN-117024658-A | Phospholipid terminal functionalized rare earth isoprene rubber and preparation method and application thereof | 海南天然橡胶产业集团股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-109897156-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109897224-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109897221-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109897220-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109897164-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109897149-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109897219-A | A kind of reactive flame retardant and its preparation method and application | 广东广山新材料股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| US-20020137921-A1 | Oligonucleotides having chiral phosphorus linkages | COOK PHILLIP DAN (US) | 2002-09-26 | — | — | US | disclosed |
| EP-0655088-B1 | OLIGONUCLEOTIDES HAVING CHIRAL PHOSPHORUS LINKAGES | ISIS PHARMACEUTICALS INC (US) | 2002-07-24 | — | — | EP | disclosed |
| US-20010008936-A1 | Oligonucleotides having chiral phosphorus linkages | ISIS PHARMACEUTICALS, INC. | 2001-07-19 | — | — | US | disclosed |
| US-6239265-B1 | FOR RESEARCH AND DIAGNOSIS | ISIS PHARMACEUTICALS, INC. | 2001-05-29 | — | — | US | disclosed |
| US-5852188-A | Oligonucleotides having chiral phosphorus linkages | ISIS PHARMACEUTICALS, INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-5521302-A | NUCLEOPHILIC REACTION OF PHOSPHATE GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0655088-A1 | OLIGONUCLEOTIDES HAVING CHIRAL PHOSPHORUS LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1995-05-31 | — | — | EP | disclosed |
| US-5212295-A | Monomers for preparation of oligonucleotides having chiral phosphorus linkages | ISIS PHARMACEUTICALS (US) | 1993-05-18 | — | — | US | disclosed |
| WO-1993008296-A1 | OLIGONUCLEOTIDES HAVING CHIRAL PHOSPHORUS LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1993-04-29 | — | — | WO | disclosed |
| US-5010201-A | Process for the preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |