Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK1 | P57059 | 1/20 | 0.51 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.51 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749200 | 1.00 | SIK1 (0.51) | SIK1SIK2SIK3MAPTHPGD | |
| SCHEMBL6752626 | 0.90 | HPGD (0.49) | SIK1SIK2SIK3MAPTHPGD | |
| SCHEMBL6752628 | 0.90 | HPGD (0.49) | SIK1SIK2SIK3MAPTHPGD | |
| SCHEMBL2649783 | 0.90 | HPGD (0.48) | SIK1SIK2SIK3HPGDRAB9A | |
| SCHEMBL2649781 | 0.90 | HPGD (0.48) | SIK1SIK2SIK3HPGDRAB9A | |
| SCHEMBL6752611 | 0.81 | FGFR1 (0.67) | SIK1SIK2SIK3HPGDRAB9A | |
| SCHEMBL2648809 | 0.80 | HPGD (0.48) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL2648805 | 0.80 | HPGD (0.48) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL2648975 | 0.80 | HPGD (0.48) | HPGDKMT2ARAB9AABCB1ALDH1A1 | |
| SCHEMBL2648980 | 0.80 | HPGD (0.48) | HPGDKMT2ARAB9AABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710044-B2 | Technical field | NEUROSEARCH A/S (DK) | 2004-03-23 | — | — | US | claimed |