Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.45 |
| ▸ | CFB | P00751 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364559 | 0.80 | NISCH (0.47) | NISCHGAATSHRADRA1ALMNA | |
| SCHEMBL4819258 | 0.77 | NISCH (0.52) | NISCHSMN1; SMN2NLRP3GAATSHR | |
| SCHEMBL4360889 | 0.75 | NISCH (0.58) | NISCHGAATSHRADRA1ALMNA | |
| SCHEMBL4819055 | 0.74 | NISCH (0.45) | NISCHSMN1; SMN2NLRP3GAATSHR | |
| SCHEMBL14027009 | 0.73 | NISCH (0.50) | NISCHGAATSHRADRA1ALMNA | |
| SCHEMBL4825416 | 0.73 | NISCH (0.56) | NISCHADRA1ALMNAHTR1AADRA2A | |
| SCHEMBL4821104 | 0.72 | NISCH (0.51) | NISCHGAATSHRADRA1ALMNA | |
| SCHEMBL4158125 | 0.71 | NISCH (0.53) | NISCHSMN1; SMN2NLRP3GAATSHR | |
| SCHEMBL4360835 | 0.71 | NISCH (0.53) | NISCHSMN1; SMN2 | |
| SCHEMBL4365831 | 0.70 | NISCH (0.55) | NISCHGAATSHRADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |