SCHEMBL6750319

SCHEMBL6750319

[c]1scc2c1-c1ccccc1-2

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
CES2 O00748 1/20 0.32
APAF1 O14727 1/20 0.32
TERT O14746 1/20 0.32
NPC1 O15118 1/20 0.32
PLIN1 O60240 1/20 0.32
TDP2 O95551 1/20 0.32
S1PR4 O95977 1/20 0.32
LMNA P02545 1/20 0.32
PLA2G1B P04054 1/20 0.32
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32
PTPRC P08575 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
PLCG1 P19174 1/20 0.32
MAOA P21397 1/20 0.32
S1PR1 P21453 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10407470 0.64 NPC1 (0.36) NPC1RAB9ASMN1; SMN2
SCHEMBL29711875 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL29543474 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL28904690 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL58152 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL49870 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL29067593 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL28694051 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL11875421 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT
SCHEMBL4368339 0.63 MEN1 (0.61) KDM4EMEN1CES2APAF1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699621-B2 ELECTROPOLYMERIZING MONOMERS ON TO A SUBSTRATE IN A POLYMERIZATION SOLUTION; ELECTROCHEMICALLY CONDITIONING POLYMER SO AS TO INCREASE DISCHARGE EFFICIENCY AND CHARGE CAPACITY; DOPING TO IMPART A NON-NEUTRAL CHARGE JOHNS HOPKINS UNIVERSITY 2004-03-02 US claimed
US-20030143461-A1 METHOD FOR ELECTROCHEMICAL CONDITIONING POLYMERIC ELECTRODEDS JOHNS HOPKINS UNIVERSITY 2003-07-31 US claimed
WO-2000041255-A1 METHOD FOR ELECTROCHEMICAL CONDITIONING POLYMERIC ELECTRODES JOHNS HOPKINS UNIVERSITY (US) 2000-07-13 WO claimed