Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.47 |
| ▸ | TYMP | P19971 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750388 | 1.00 | DPYD (0.47) | DPYDTYMPATAD2PDE5AGAA | |
| SCHEMBL7599202 | 0.83 | DPYD (0.46) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL8916616 | 0.83 | DPYD (0.46) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL8918100 | 0.80 | DPYD (0.50) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL7602267 | 0.80 | DPYD (0.50) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL7602259 | 0.80 | DPYD (0.50) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL7603321 | 0.80 | DPYD (0.50) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL7604157 | 0.76 | DPYD (0.53) | DPYDATAD2GAAALDH1A1LMNA | |
| SCHEMBL6374582 | 0.73 | DPYD (0.59) | DPYDTYMPATAD2GAAALDH1A1 | |
| SCHEMBL6374591 | 0.73 | DPYD (0.59) | DPYDTYMPATAD2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983290-B1 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | MORPHOCHEM AG (DE) | 2004-03-03 | — | — | EP | claimed |
| US-6355726-B1 | MULTICOMPONENT UGI REACTION; ANTISENSE AGENTS, ANTIGENS; DIAGNOSIS; CONTROLLING GENE EXPRESSION BY POLYMERIC PEPTIDE NUCLEIC ACIDS | MORPHOCHEM AG (DE) | 2002-03-12 | — | — | US | claimed |
| JP-2002500643-A | — | — | 2002-01-08 | — | — | JP | claimed |
| EP-0983290-A1 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | Morphochem AG (DE) | 2000-03-08 | — | — | EP | claimed |
| WO-1998051697-A2 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | MORPHOCHEM AG (DE) | 1998-11-19 | — | — | WO | claimed |
| EP-0983290-B1 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | MORPHOCHEM AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6355726-B1 | MULTICOMPONENT UGI REACTION; ANTISENSE AGENTS, ANTIGENS; DIAGNOSIS; CONTROLLING GENE EXPRESSION BY POLYMERIC PEPTIDE NUCLEIC ACIDS | MORPHOCHEM AG (DE) | 2002-03-12 | — | — | US | disclosed |
| EP-0983290-A1 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | Morphochem AG (DE) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998051697-A2 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | MORPHOCHEM AG (DE) | 1998-11-19 | — | — | WO | disclosed |