Propazine

Propazine

SCHEMBL67521

CC(C)Nc1nc(Cl)nc(NC(C)C)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 1.00
TDP1 Q9NUW8 2/20 1.00
POLB P06746 1/20 0.54
HTT P42858 3/20 0.52
LMNA P02545 3/20 0.52
MAPK1 P28482 2/20 0.52
F2 P00734 1/20 0.52
ALDH1A1 P00352 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
KMT2A Q03164 4/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 2/20 0.48
CYP1A2 P05177 1/20 0.48
KCNH3 Q9ULD8 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propazine SCHEMBL8539531 1.00 GAA (1.00) GAATDP1POLBHTTLMNA
SCHEMBL1923400 0.95 GAA (0.90) GAATDP1POLBHTTLMNA
SCHEMBL2684956 0.91 GAA (0.83) GAATDP1POLBHTTLMNA
SCHEMBL2492890 0.89 GAA (0.79) GAATDP1POLBHTTLMNA
SCHEMBL20814490 0.86 GAA (0.75) GAATDP1POLBHTTLMNA
SCHEMBL8041736 0.86 GAA (0.74) GAATDP1HTTLMNAMAPK1
Atrazine SCHEMBL9117361 0.85 GAA (0.73) GAATDP1POLBHTTLMNA
Atrazine SCHEMBL20723465 0.85 GAA (0.73) GAATDP1POLBHTTLMNA
SCHEMBL2491780 0.85 GAA (0.73) GAATDP1POLBHTTLMNA
Atrazine SCHEMBL1516439 0.85 GAA (0.73) GAATDP1POLBHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13003 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
US-12462268-B2 Method for assessing disparate impact in internet markets UNIVERSITY OF SOUTH CAROLINA (US) 2025-11-04 US claimed
US-20250318528-A1 HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-16 US claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-4601471-A1 SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES Corteva Agriscience LLC (US) 2025-08-20 EP claimed
EP-4593598-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND BEFLUBUTAMID FMC Corporation (US) 2025-08-06 EP claimed
US-12376586-B2 Microcapsules comprising cinmethyln in the core and a polyurea derived from diphenylmethane diisocyanate or an oligomer thereof BASF Agro B.V. (NL) 2025-08-05 US claimed
US-4824475-A CONTAINING GLYCOL SULFONATE OR SULFAMATE THE DOW CHEMICAL COMPANY (US) 1989-04-25 US claimed
EP-0063867-B1 FLOWABLE COMPOSITIONS COMPRISING 2-CHLORO-N-ISOPROPYLACETANILIDE AND S-TRIAZINE HERBICIDES MONSANTO COMPANY (US) 1984-12-19 EP claimed
US-4417916-A POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE, POLYUREA, LIGNIN MONSANTO COMPANY (US) 1983-11-29 US claimed
US-4411692-A PROPACHLOR AND S-TRIAZINES MONSANTO COMPANY (US) 1983-10-25 US claimed
EP-0010972-B1 FLOWABLE HERBICIDES CONTAINING PROPACHLOR AND A PROCESS FOR THEIR PREPARATION MONSANTO COMPANY (US) 1982-11-24 EP claimed
EP-0063867-A1 Flowable compositions comprising 2-chloro-N-isopropylacetanilide and s-triazine herbicides MONSANTO COMPANY (US) 1982-11-03 EP claimed
US-4256481-A Selective herbicide compositions NITROKEMIA IPARTELEPEK (HU) 1981-03-17 US claimed
US-4186265-A BY EXTRACTION WITH AQUEOUS ACID OR BY ACIDIFICATION OF ALKALINE FILTRATE FOLLOWED BY EXTRACTION WITH WATER-IMMISCIBLE SOLVENT CIBA-GEIGY CORPORATION (US) 1980-01-29 US claimed
US-4099006-A PROCESS FOR THE PRODUCTION OF CHLORO-AMINO-S-TRIAZINES RUMIANCA S.P.A. (IT) 1978-07-04 US claimed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US claimed