Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756781 | 1.00 | DYRK1A (0.52) | DYRK1AGSK3BPLK1EGFRHDAC8 | |
| SCHEMBL6754365 | 1.00 | DYRK1A (0.52) | DYRK1AGSK3BPLK1EGFRHDAC8 | |
| SCHEMBL6756795 | 0.87 | MAPT (0.56) | DYRK1AGSK3BSMN1; SMN2NPC1MAPT | |
| SCHEMBL6756792 | 0.87 | MAPT (0.56) | DYRK1AGSK3BSMN1; SMN2NPC1MAPT | |
| SCHEMBL6760171 | 0.84 | DYRK1A (0.48) | DYRK1AGSK3BSMN1; SMN2NPC1MAPT | |
| SCHEMBL6760166 | 0.84 | DYRK1A (0.48) | DYRK1AGSK3BSMN1; SMN2NPC1MAPT | |
| Hydrochloric Acid SCHEMBL7457570 | 0.84 | MAOB (0.58) | DYRK1AGSK3BEGFRSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7457576 | 0.84 | MAOB (0.58) | DYRK1AGSK3BEGFRSMN1; SMN2NPC1 | |
| SCHEMBL6756808 | 0.83 | GSK3B (0.65) | DYRK1AGSK3BEGFRSMN1; SMN2NPC1 | |
| SCHEMBL6756807 | 0.83 | GSK3B (0.65) | DYRK1AGSK3BEGFRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | DYRK1A 3409/4885GSK3B 4671/4885PLK1 2665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.