Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51558 | 0.95 | TSHR (0.56) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL9447790 | 0.90 | TSHR (0.43) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL28025837 | 0.90 | TSHR (0.50) | TSHRHPGDTHRBATMALDH1A1 | |
| SCHEMBL11743891 | 0.89 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL10584690 | 0.89 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL21381448 | 0.89 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL10718051 | 0.89 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL2037179 | 0.89 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL147629 | 0.88 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL648612 | 0.87 | TSHR (0.51) | TSHRHPGDTHRBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092659-A1 | Amphipathic polymer particles and methods of manufacturing the same | GANAPATHIAPPAN SIVAPACKIA (US) | 2004-05-13 | — | — | US | disclosed |