SCHEMBL6755477

SCHEMBL6755477

FC(F)(F)C1(C2(F)C(F)(F)C(F)(F)C(F)(F)C3(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C32F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997087 0.88 MEN1 (0.47) MEN1KMT2ATDP1
SCHEMBL11612420 0.88 MEN1 (0.44) MEN1KMT2ATDP1
SCHEMBL8402370 0.88 MEN1 (0.44) MEN1KMT2ATDP1
SCHEMBL18496394 0.78 MEN1 (0.38) MEN1KMT2ATDP1
SCHEMBL1524186 0.75 MEN1 (0.35) MEN1KMT2ATDP1
Perflunafene SCHEMBL7058440 0.73 MEN1 (0.73) MEN1KMT2ATDP1
Perflunafene SCHEMBL2509418 0.73 MEN1 (0.73) MEN1KMT2ATDP1
SCHEMBL18979331 0.73 MEN1 (0.89) MEN1KMT2ATDP1
Perflunafene SCHEMBL21916758 0.73 MEN1 (0.89) MEN1KMT2ATDP1
SCHEMBL9316445 0.73 MEN1 (0.50) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3498144-B2 2004-02-16 JP claimed
EP-0732353-B1 Adhesion of a fluoropolymer to a surface DU PONT (US) 2000-04-26 EP claimed
EP-0656910-B1 PURIFICATION OF FLUOROPOLYMERS DU PONT (US) 1997-01-22 EP claimed
EP-0732353-A2 Adhesion of a fluoropolymer to a surface E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-18 EP claimed
EP-0656910-A1 PURIFICATION OF FLUOROPOLYMERS. DU PONT (US) 1995-06-14 EP claimed
WO-1994005706-A2 PURIFICATION OF FLUOROPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-17 WO claimed
US-5237049-A Solvent extraction with perfluorocycloalkane E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-17 US claimed
EP-0732353-B1 Adhesion of a fluoropolymer to a surface DU PONT (US) 2000-04-26 EP disclosed
EP-0656910-B1 PURIFICATION OF FLUOROPOLYMERS DU PONT (US) 1997-01-22 EP disclosed
EP-0732353-A2 Adhesion of a fluoropolymer to a surface E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-18 EP disclosed
EP-0656910-A1 PURIFICATION OF FLUOROPOLYMERS. DU PONT (US) 1995-06-14 EP disclosed
WO-1994005706-A2 PURIFICATION OF FLUOROPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-17 WO disclosed
US-5237049-A Solvent extraction with perfluorocycloalkane E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-17 US disclosed