Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727637 | 0.76 | HCRTR1 (0.54) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL2878189 | 0.76 | SCN1A (0.59) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL3698223 | 0.70 | HCRTR1 (0.58) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL8561210 | 0.70 | HCRTR1 (0.51) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL3680789 | 0.70 | CYP3A4 (0.64) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL878485 | 0.69 | CA1 (0.61) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL6580093 | 0.69 | CA1 (0.61) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL13979927 | 0.69 | HTT (0.64) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28302205 | 0.69 | HCRTR1 (0.50) | HCRTR1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL11154008 | 0.69 | TSHR (0.58) | HCRTR1ALDH1A1HTR6TSHRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713473-B1 | 6-CARBAMATE-1,2,3,4-TETRAHYDROCARBAZOLE DERIVATIVES; AFFINITY FOR NEUROPEPTIDE Y RECEPTORS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1184373-A1 | TRICYCLIC COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |